Southwest of Salem excavates the nightmarish persecution of Elizabeth Ramirez, Cassandra Rivera, Kristie Mayhugh, and Anna Vasquez — four Latina lesbians wrongfully convicted of allegedly gang raping two little girls. This bizarre case is the first to be adjudicated under momentous new legislation: for the first time in U.S. history, wrongfully convicted innocents can challenge convictions based on debunked scientific evidence. The film also unravels the sinister interplay of mythology, homophobia, and prosecutorial fervor which led to this modern day witch hunt.